RNU6-341P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-341P RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated RNU6-341P data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher RNU6-341P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-341P expression acts as an unfavorable survival marker, although some lineages such as LAML and UCS show a favorable association.

THCA, KIRC, and UCEC are the cancer types where RNU6-341P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
THCADFSTertileAll0.7380.942<.00168view →
KIRCDFSTertileAll0.5090.684<.00159view →
UCECDFSMedianAll0.5570.689.00448view →
COADDFSTertileAll0.2990.617<.00137view →
LAMLDFSQuartileAll0.7360.398<.00136view →
UCSDFSTertileIV0.8320.239.02424view →
KIRPOSTertileAll0.9000.984.00222view →
READDFSTertileIV0.2860.711.00121view →
UVMDFSMedianIII,IV0.2570.612.00319view →
ACCOSMedianIV0.7770.309.01918view →
THYMDFSMedianAll0.7470.972.00717view →
PAADDFSMedianAll0.5600.377.01716view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

RNU6-341P–THCA (DFS)

Kaplan–Meier survival curve for RNU6-341P RNA-high vs -low samples in THCA.

Open the THCA breakdown →

Exploration