RNU6-341P

Across TCGA pan-cancer cohorts, RNU6-341P RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of RNU6-341P’s most consistent transcriptional readouts.

The strongest signal is observed in cholangiocarcinoma (CHOL), where RNU6-341P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU6-341P is over-expressed in tumor.

CHOL, BLCA, and BRCA are the cancer types where RNU6-341P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-341P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
CHOL	All	All	+0.932	.011	4	view →
BLCA	All	All	+0.655	.008	4	view →
BRCA	Female	All	+0.359	.011	4	view →
HNSC	All	III,IV	+0.159	.041	3	view →
UCEC	All	All	+0.463	.009	2	view →
LUAD	All	All	+0.474	.023	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

RNU6-341P–CHOL

Open the CHOL breakdown →