RNU6-322P

Across TCGA pan-cancer cohorts, RNU6-322P RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated RNU6-322P data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher RNU6-322P RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RNU6-322P expression acts as an unfavorable survival marker, although some lineages such as BLCA and BRCA show a favorable association.

BLCA, KICH, and LIHC are the cancer types where RNU6-322P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Quartile	II,III,IV	0.424	0.276	.008	38	view →
KICH	DFS	Median	II,III,IV	0.679	1.000	.022	27	view →
LIHC	DFS	Quartile	II,III,IV	0.138	0.423	.010	14	view →
BRCA	OS	Median	III,IV	0.633	0.453	.023	8	view →
SKCM	OS	Median	All	0.372	0.268	.006	8	view →
OV	DFS	Tertile	All	0.414	0.339	.025	8	view →
THCA	OS	Quartile	All	0.858	0.989	.009	7	view →
LUSC	OS	Tertile	III,IV	0.577	0.817	.013	7	view →
LUAD	OS	Tertile	All	0.849	0.710	.010	7	view →
COAD	DFS	Median	III,IV	0.739	0.545	.012	6	view →
CESC	OS	Median	All	0.680	0.486	.014	6	view →
LAML	DFS	Quartile	All	0.325	0.738	.015	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

RNU6-322P–BLCA (DFS)

Open the BLCA breakdown →