RNU6-314P

Across TCGA patient cohorts, RNU6-314P RNA expression is significantly associated with the go_rna of many other GO terms, with 5,765 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU6-314P-associated GO terms across cancer lineages are Negative regulation of stem cell differentiation, Transport along microtubule, and Pro-B cell differentiation. Each is linked with RNU6-314P in more than 13 cancer types. Because this analysis shows association rather than direction, both RNU6-314P-to-partner and partner-to-RNU6-314P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of stem cell differentiation grouped by RNU6-314P-low versus RNU6-314P-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-314P→partner) and Y-score (partner→RNU6-314P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Negative regulation of stem cell differentiation →	+0.069	+0.594	<.001	<.001	3	14
ESCA	Transport along microtubule →	+0.040	+0.420	<.001	<.001	3	13
THYM	Pro-B cell differentiation →	+0.067	+0.175	<.001	<.001	3	13
ESCA	Cytoskeleton-dependent intracellular transport →	+0.040	+0.470	<.001	<.001	3	13
STAD	Obsolete ncRNA catabolic process →	+0.041	+0.298	<.001	<.001	3	13
STAD	Macromolecule methylation →	+0.040	+0.382	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,765 associations by consensus.

Negative regulation of stem cell differentiation by RNU6-314P expression — ESCA

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