RNU6-314P

Across TCGA pan-cancer cohorts, RNU6-314P RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated RNU6-314P data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher RNU6-314P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-314P expression acts as an unfavorable survival marker, although some lineages such as LAML and GBM show a favorable association.

UVM, CHOL, and LUSC are the cancer types where RNU6-314P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	All	0.574	0.866	.008	108	view →
CHOL	OS	Tertile	II,III,IV	0.089	0.712	.001	72	view →
LUSC	DFS	Tertile	All	0.552	0.682	.007	42	view →
KICH	DFS	Tertile	II,III,IV	0.521	0.950	.006	36	view →
ACC	DFS	Tertile	II,III,IV	0.078	0.593	.003	33	view →
SKCM	DFS	Tertile	All	0.342	0.660	<.001	30	view →
PAAD	DFS	Tertile	All	0.306	0.499	.014	27	view →
SARC	DFS	Tertile	All	0.435	0.629	.002	27	view →
MESO	OS	Tertile	IV	0.077	0.592	.019	27	view →
THCA	OS	Tertile	IV	0.546	0.917	.004	21	view →
LIHC	OS	Tertile	All	0.521	0.789	.010	21	view →
READ	OS	Tertile	IV	0.077	1.000	.014	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

RNU6-314P–UVM (OS)

Open the UVM breakdown →