RNU6-312P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-312P RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated RNU6-312P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU6-312P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-312P expression acts as an unfavorable survival marker, although some lineages such as BLCA and UCS show a favorable association.

KIRC, BLCA, and STAD are the cancer types where RNU6-312P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCDFSMedianAll0.5130.697<.00191view →
BLCADFSQuartileAll0.4280.222.00169view →
STADDFSMedianII,III,IV0.4250.618<.00162view →
UVMDFSTertileIII,IV0.2110.795.00161view →
UCSDFSMedianIV0.9520.367.00128view →
ACCOSMedianII,III,IV0.8580.401.00527view →
LAMLDFSTertileAll0.5660.276.00424view →
MESOOSMedianIV0.2640.759.00221view →
ESCAOSTertileIV0.2190.856.02418view →
CESCDFSTertileAll0.7430.874.00118view →
KICHOSTertileIII,IV0.4670.934.01117view →
LUADOSQuartileII,III,IV0.5270.347.00716view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

Exploration