Across TCGA pan-cancer cohorts, RNU6-312P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RNU6-312P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where RNU6-312P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-312P is over-expressed in tumor, although a few such as KICH and BRCA show the opposite, repressed pattern.

KICH, KIRC, and CHOL are the cancer types where RNU6-312P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-312P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	II,III,IV	−0.598	.002	8	view →
KIRC	All	All	+0.387	<.001	5	view →
CHOL	All	All	+1.477	<.001	3	view →
THCA	All	All	+0.501	.004	2	view →
BRCA	Female	All	−0.388	.002	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: RNU6-312P RNA expression & survival · all RNU6-312P data types