RNU6-301P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-301P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RNU6-301P data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher RNU6-301P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-301P expression acts as an unfavorable survival marker, although some lineages such as LUAD and LUSC show a favorable association.

COAD, READ, and KIRC are the cancer types where RNU6-301P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
COADOSTertileAll0.6050.818<.001108view →
READDFSTertileIV0.0550.646<.00172view →
KIRCDFSQuartileIII,IV0.2690.534.00155view →
LUADDFSTertileIII,IV0.8890.589.00651view →
MESOOSTertileAll0.0840.560<.00145view →
UVMDFSTertileAll0.1480.776<.00145view →
KIRPOSTertileIV0.1110.503<.00136view →
CHOLOSTertileII,III,IV0.2530.796.01836view →
ACCDFSTertileIII,IV0.0570.471.00318view →
LUSCOSMedianAll0.8140.634.00917view →
ESCAOSTertileAll1.0000.456.01114view →
PAADOSTertileAll0.2130.435.0314view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

Exploration