RNU6-277P

Across TCGA pan-cancer cohorts, RNU6-277P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated RNU6-277P data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher RNU6-277P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-277P expression acts as an unfavorable survival marker, although some lineages such as LGG and PAAD show a favorable association.

LIHC, LGG, and PAAD are the cancer types where RNU6-277P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Tertile	All	0.167	0.712	<.001	39	view →
LGG	DFS	Tertile	All	0.827	0.651	<.001	34	view →
PAAD	DFS	Tertile	All	0.663	0.315	.016	33	view →
OV	DFS	Tertile	IV	0.137	0.469	.010	18	view →
GBM	DFS	Quartile	All	0.535	0.291	.007	15	view →
STAD	DFS	Tertile	II,III,IV	0.402	0.701	.013	12	view →
SARC	OS	Tertile	All	0.606	0.757	.008	12	view →
THCA	DFS	Tertile	III,IV	0.684	0.931	.014	9	view →
SKCM	DFS	Quartile	IV	0.040	0.591	.008	6	view →
PCPG	OS	Quartile	All	0.893	0.986	.036	3	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

RNU6-277P–LIHC (OS)

Open the LIHC breakdown →