RNU6-277P

Across TCGA pan-cancer cohorts, RNU6-277P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RNU6-277P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RNU6-277P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU6-277P is over-expressed in tumor, although a few such as BRCA and COAD show the opposite, repressed pattern.

KIRC, BRCA, and COAD are the cancer types where RNU6-277P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-277P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.438	<.001	9	view →
BRCA	Female	All	−0.658	<.001	6	view →
COAD	All	II,III,IV	−0.112	.020	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

RNU6-277P–KIRC

Open the KIRC breakdown →