Across TCGA patient cohorts, RNU6-253P RNA expression is significantly associated with the go_rna of many other GO terms, with 1,325 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU6-253P-associated GO terms across cancer lineages are DNA integration, Negative regulation of DNA binding, and Positive regulation of developmental growth. Each is linked with RNU6-253P in more than 2 cancer types. Because this analysis shows association rather than direction, both RNU6-253P-to-partner and partner-to-RNU6-253P results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-253P→partner) and Y-score (partner→RNU6-253P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	DNA integration →	+0.087	+0.055	<.001	.003	3	2
STAD	Negative regulation of DNA binding →	+0.196	+0.084	<.001	.004	3	2
STAD	Positive regulation of developmental growth →	+0.112	+0.053	<.001	.005	3	2
STAD	Regulation of peptidyl-tyrosine phosphorylation →	+0.138	+0.094	<.001	.008	2	3
STAD	Positive regulation of dendritic spine development →	+0.118	+0.090	<.001	.003	3	2
STAD	Amino acid metabolic process →	+0.173	+0.060	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,325 associations by consensus.

Exploration

RNU6-253P survival (RNA) · tumor vs normal (RNA) · all RNU6-253P data types