RNU6-251P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-251P RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated RNU6-251P data layer.

The strongest signal is observed in cholangiocarcinoma (CHOL), where higher RNU6-251P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-251P expression acts as an unfavorable survival marker.

CHOL, MESO, and READ are the cancer types where RNU6-251P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CHOLOSTertileIII,IV0.1620.915.00463view →
MESOOSTertileIII,IV0.0690.580<.00154view →
READDFSTertileIV0.1410.671<.00148view →
LAMLDFSQuartileAll0.3100.515.00636view →
KICHDFSTertileAll0.4360.921.00134view →
ESCAOSTertileII,III,IV0.4641.000.00631view →
PAADOSTertileAll0.2280.478.01127view →
KIRPDFSTertileAll0.3380.684.01027view →
LUADOSTertileIII,IV0.2220.531.0409view →
SKCMOSTertileIV0.4150.861.0149view →
LGGDFSTertileAll0.1760.456.0176view →
BLCAOSTertileIV0.3600.613.0333view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

Exploration