RNU6-250P

Across TCGA pan-cancer cohorts, RNU6-250P RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated RNU6-250P data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher RNU6-250P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-250P expression acts as an unfavorable survival marker, although some lineages such as BLCA show a favorable association.

LIHC, HNSC, and KIRC are the cancer types where RNU6-250P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Tertile	II,III,IV	0.483	0.748	<.001	87	view →
HNSC	OS	Tertile	III,IV	0.202	0.679	.003	75	view →
KIRC	OS	Tertile	II,III,IV	0.144	0.558	.001	60	view →
STAD	OS	Tertile	IV	0.074	0.496	.002	48	view →
SKCM	DFS	Tertile	III,IV	0.113	0.654	.002	39	view →
BRCA	DFS	Quartile	All	0.866	0.912	.008	38	view →
UCS	DFS	Tertile	IV	0.132	0.718	.002	36	view →
UCEC	OS	Tertile	All	0.766	0.930	<.001	36	view →
LUSC	OS	Tertile	III,IV	0.284	0.698	.002	36	view →
BLCA	DFS	Tertile	All	0.834	0.449	.021	18	view →
ESCA	OS	Tertile	All	0.240	0.566	.018	18	view →
THCA	OS	Tertile	III,IV	0.214	0.861	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

RNU6-250P–LIHC (OS)

Open the LIHC breakdown →