RNU6-250P

associated omics data
RNA, U6 small nuclear 250, pseudogeneGenealiases: []

Q-omics provides the consensus-scored RNU6-250P profile across patient tissues and cancer cell-line models. RNU6-250P expression is associated with patient survival in 12 of 34 cancer types, with the highest sampling consensus in LIHC. Among the 18 cancer types available for tumor–normal comparison, RNU6-250P is differentially expressed in 1, with the highest sampling consensus in BRCA. Additionally, RNU6-250P RNA expression shows 7,644 significant gene co-expression associations, with the highest sampling consensus in COAD. Together, these results highlight LIHC, BRCA, and COAD as cancer lineages where RNU6-250P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes RNU6-250P survival associations across molecular data types. RNU6-250P RNA expression shows survival associations in the most cancer types (12). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
RNU6-250P data typeSurvival analysisLineage consensusLineage of highest sampling consensus
RNAKaplan–Meier12LIHC (87)view →
This table ranks reproducible RNU6-250P RNA expression–survival associations across cancer types. High RNU6-250P expression shows unfavorable associations in LIHC, HNSC, KIRC, STAD, SKCM and BRCA. The LIHC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LIHC as the clearest survival context for RNU6-250P RNA expression.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LIHCOSTertileII,III,IV0.4830.748<.00187view →
HNSCOSTertileIII,IV0.2020.679.00375view →
KIRCOSTertileII,III,IV0.1440.558.00160view →
STADOSTertileIV0.0740.496.00248view →
SKCMDFSTertileIII,IV0.1130.654.00239view →
BRCADFSQuartileAll0.8660.912.00838view →
Pink = unfavorable, green = favorable. all 12 lineages →

RNU6-250P-LIHC (OS)

Kaplan–Meier survival curve for RNU6-250P RNA expression in LIHC: high vs low expression groups.

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Tumor vs Normal expression

This table summarizes RNU6-250P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in BRCA for RNA.
RNU6-250P data typeExpression analysisLineage consensusLineage of highest sampling consensus
RNABox plot1BRCA (6)view →
This table ranks reproducible tumor–normal expression differences for RNU6-250P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU6-250P shows higher tumor expression in BRCA. The BRCA box plot shows higher RNU6-250P RNA expression in tumor versus normal tissue (log2 FC = +0.288, t-test p < 0.001).
LineageGenderStageFold-changepSampling consensus
BRCAFemaleII,III,IV+0.288<.0016view →
Green = repressed in tumor. all 1 lineages →

RNU6-250P-BRCA

Tumor-vs-normal expression box plot for RNU6-250P in BRCA.

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Cross-omics associations

This table shows molecular features associated with RNU6-250P in patient tissues and cancer cell lines. In patient samples, RNU6-250P shows the broadest associations at the RNA and protein expression levels, with COAD recurring as the lineage with the largest associated feature set.
Associated data typeStrength (# associated data)Lineage of highest associated data
RNA
RNA7,644COAD (2176)view →
Function (RNA)5,499STAD (3446)view →