RNU6-221P

Across TCGA patient cohorts, RNU6-221P RNA expression is significantly associated with the go_rna of many other GO terms, with 5,746 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU6-221P-associated GO terms across cancer lineages are Response to ionizing radiation, Response to UV-C, and Exit from mitosis. Each is linked with RNU6-221P in more than 2 cancer types. Because this analysis shows association rather than direction, both RNU6-221P-to-partner and partner-to-RNU6-221P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to ionizing radiation grouped by RNU6-221P-low versus RNU6-221P-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-221P→partner) and Y-score (partner→RNU6-221P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Response to ionizing radiation →	+0.135	+0.178	<.001	<.001	3	2
STAD	Response to UV-C →	+0.102	+0.146	<.001	<.001	3	2
STAD	Exit from mitosis →	+0.138	+0.200	<.001	<.001	3	2
STAD	Regulation of gastrulation →	+0.093	+0.184	<.001	<.001	3	2
STAD	Neuron projection organization →	+0.097	+0.206	<.001	<.001	3	2
STAD	tRNA surveillance →	+0.107	+0.179	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,746 associations by consensus.

Response to ionizing radiation by RNU6-221P expression — STAD

Explore this box plot interactively →