RNU6-221P

Q-omics provides the consensus-scored RNU6-221P profile across patient tissues and cancer cell-line models. RNU6-221P expression is associated with patient survival in 3 of 34 cancer types, with the highest sampling consensus in KIRC. Additionally, RNU6-221P RNA expression shows 5,746 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight KIRC, and STAD as cancer lineages where RNU6-221P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes RNU6-221P survival associations across molecular data types. RNU6-221P RNA expression shows survival associations in the most cancer types (3). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

RNU6-221P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	3	KIRC (54)	view →

This table ranks reproducible RNU6-221P RNA expression–survival associations across cancer types. High RNU6-221P expression shows unfavorable associations in KIRC, SARC and STAD. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for RNU6-221P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.248	0.799	<.001	54	view →
SARC	DFS	Tertile	All	0.095	0.632	.002	18	view →
STAD	OS	Tertile	III,IV	0.162	0.506	.046	9	view →

Pink = unfavorable, green = favorable. all 3 lineages →

RNU6-221P-KIRC (DFS)

Explore this curve interactively →