RNU6-180P

Across TCGA pan-cancer cohorts, RNU6-180P RNA is linked to patient survival in 5 of 34 cancer types, making it the most broadly survival-associated RNU6-180P data layer.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher RNU6-180P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-180P expression acts as an unfavorable survival marker, although some lineages such as STAD show a favorable association.

ESCA, LUSC, and THCA are the cancer types where RNU6-180P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Tertile	II,III,IV	0.164	0.702	.003	63	view →
LUSC	OS	Tertile	All	0.005	0.762	<.001	36	view →
THCA	OS	Tertile	All	0.323	0.955	<.001	24	view →
STAD	DFS	Tertile	III,IV	0.799	0.307	.029	24	view →
HNSC	OS	Tertile	IV	0.001	0.643	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RNU6-180P–ESCA (OS)

Open the ESCA breakdown →