Q-omics provides the consensus-scored RNU6-180P profile across patient tissues and cancer cell-line models. RNU6-180P expression is associated with patient survival in 5 of 34 cancer types, with the highest sampling consensus in ESCA. Additionally, RNU6-180P RNA expression shows 9,412 significant gene co-expression associations, with the highest sampling consensus in LUSC. Together, these results highlight ESCA, and LUSC as cancer lineages where RNU6-180P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes RNU6-180P survival associations across molecular data types. RNU6-180P RNA expression shows survival associations in the most cancer types (5). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

RNU6-180P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	5	ESCA (63)	view →

This table ranks reproducible RNU6-180P RNA expression–survival associations across cancer types. High RNU6-180P expression shows unfavorable associations in ESCA, LUSC, THCA and HNSC, but favorable associations in STAD. The ESCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .003). Together, the overview and detailed table identify ESCA as the clearest survival context for RNU6-180P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Tertile	II,III,IV	0.164	0.702	.003	63	view →
LUSC	OS	Tertile	All	0.005	0.762	<.001	36	view →
STAD	DFS	Tertile	III,IV	0.799	0.307	.029	24	view →
THCA	OS	Tertile	All	0.323	0.955	<.001	24	view →
HNSC	OS	Tertile	IV	0.001	0.643	<.001	18	view →

Pink = unfavorable, green = favorable. all 5 lineages →

RNU6-180P-ESCA (OS)

Kaplan–Meier survival curve for RNU6-180P RNA expression in ESCA: high vs low expression groups.

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Cross-omics associations

This table shows molecular features associated with RNU6-180P in patient tissues and cancer cell lines. In patient samples, RNU6-180P shows the broadest associations at the RNA and protein expression levels, with LUSC recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	9,412	LUSC (4208)	view →
Function (RNA)	5,815	STAD (5313)	view →