RNU6-178P

Across TCGA pan-cancer cohorts, RNU6-178P RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RNU6-178P data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher RNU6-178P RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RNU6-178P expression acts as an unfavorable survival marker, although some lineages such as BLCA and ACC show a favorable association.

BLCA, ACC, and CHOL are the cancer types where RNU6-178P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Tertile	All	0.703	0.468	<.001	138	view →
ACC	OS	Tertile	II,III,IV	1.000	0.701	.012	38	view →
CHOL	DFS	Tertile	All	0.096	0.635	.001	24	view →
UVM	OS	Tertile	II,III,IV	0.915	0.436	.018	12	view →
THYM	OS	Tertile	III,IV	0.615	1.000	.019	9	view →
PAAD	DFS	Quartile	All	0.579	0.446	.031	9	view →
LUAD	OS	Quartile	II,III,IV	0.426	0.139	.011	8	view →
SKCM	OS	Tertile	IV	1.000	0.393	.042	8	view →
UCEC	DFS	Quartile	IV	0.717	0.354	.040	8	view →
THCA	DFS	Median	III,IV	0.411	0.892	.013	6	view →
KICH	DFS	Tertile	II,III,IV	0.282	0.803	.022	6	view →
LGG	OS	Median	All	0.930	0.847	.008	5	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

RNU6-178P–BLCA (DFS)

Open the BLCA breakdown →