RNU6-171P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-171P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RNU6-171P data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RNU6-171P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-171P expression acts as an unfavorable survival marker, although some lineages such as LAML and LGG show a favorable association.

UCEC, MESO, and READ are the cancer types where RNU6-171P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECDFSTertileAll0.4750.688<.001108view →
MESOOSTertileAll0.0840.560<.00163view →
READDFSTertileIII,IV0.0820.760.00148view →
LIHCOSTertileIII,IV0.0510.650<.00136view →
PAADOSTertileII,III,IV0.3440.574.00818view →
ESCAOSQuartileAll0.5800.768.01015view →
STADOSQuartileII,III,IV0.5410.755.0239view →
THCADFSTertileIII,IV0.5560.815.0139view →
LUADOSTertileII,III,IV0.4090.572.0409view →
TGCTDFSTertileAll0.6530.824.0376view →
LAMLDFSTertileAll0.7890.511.0496view →
LGGOSTertileAll0.5950.398.0463view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

Exploration