Across TCGA pan-cancer cohorts, RNU6-1301P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RNU6-1301P’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where RNU6-1301P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-1301P is over-expressed in tumor, although a few such as LUSC and THCA show the opposite, repressed pattern.

LUSC, STAD, and THCA are the cancer types where RNU6-1301P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-1301P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	−0.289	<.001	5	view →
STAD	All	II,III,IV	+0.467	.001	4	view →
THCA	Female	All	−0.389	<.001	4	view →
BRCA	All	III,IV	−0.495	.008	2	view →
ESCA	Female	All	−0.986	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: RNU6-1301P RNA expression & survival · all RNU6-1301P data types