RNU6-1297P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1297P RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated RNU6-1297P data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher RNU6-1297P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-1297P expression acts as an unfavorable survival marker, although some lineages such as LUAD and COAD show a favorable association.

UVM, DLBC, and CHOL are the cancer types where RNU6-1297P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UVMOSTertileII,III,IV0.2130.718.00281view →
DLBCOSTertileII,III,IV0.0850.865<.00154view →
CHOLOSQuartileIII,IV0.2340.886.01745view →
KIRCDFSTertileIII,IV0.5240.679.00841view →
ACCOSTertileIII,IV0.3180.768.00136view →
KICHDFSTertileAll0.5210.969.03727view →
THCAOSTertileIV0.6261.000.00224view →
LUADDFSTertileII,III,IV0.6690.349.01019view →
COADDFSTertileIII,IV0.7290.324.02612view →
LAMLDFSQuartileAll0.4490.223.01910view →
SKCMDFSTertileIV0.0400.620.0039view →
READOSTertileIV0.4680.762.0289view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

Exploration