Across TCGA patient cohorts, RNU6-1266P mutation is significantly associated with the RNA expression of many other genes, with 30 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible RNU6-1266P-associated genes across cancer lineages are MIR6133, OR8D2, and RPL17P3. Each is linked with RNU6-1266P in more than 1 cancer types. Because this analysis shows association rather than direction, both RNU6-1266P-to-partner and partner-to-RNU6-1266P results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-1266P→partner) and Y-score (partner→RNU6-1266P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR6133 →	+0.351	+5.867	<.001	.003	3	1
SKCM	OR8D2 →	+0.036	+5.594	.002	.004	3	1
UCEC	RPL17P3 →	+0.325	+3.400	<.001	.003	3	1
UCEC	RN7SL248P →	+0.135	+4.400	<.001	.006	3	1
SKCM	CYCSP20 →	+0.113	+4.979	.006	.009	3	1
SKCM	RPL26P26 →	+0.087	+5.362	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

Exploration

RNU6-1266P survival (RNA) · tumor vs normal (RNA) · all RNU6-1266P data types