RNU6-1262P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1262P RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated RNU6-1262P data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher RNU6-1262P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-1262P expression acts as an unfavorable survival marker, although some lineages such as ACC and LIHC show a favorable association.

LUSC, KIRC, and ACC are the cancer types where RNU6-1262P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUSCDFSQuartileIII,IV0.1750.897<.00130view →
KIRCDFSMedianAll0.5140.698<.00129view →
ACCDFSTertileIII,IV0.8130.283.00820view →
THCADFSMedianIII,IV0.4070.847.01120view →
LIHCDFSTertileIII,IV0.8460.244.00318view →
SKCMDFSQuartileAll0.7000.574.00712view →
ESCADFSTertileIV0.2210.704.0249view →
HNSCDFSTertileIV0.7290.586.0188view →
LGGDFSQuartileAll0.7800.868.0157view →
UCSDFSMedianIV0.8110.514.0396view →
GBMDFSTertileAll0.4230.228.0256view →
READDFSTertileIV0.1790.936.0246view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

RNU6-1262P–LUSC (DFS)

Kaplan–Meier survival curve for RNU6-1262P RNA-high vs -low samples in LUSC.

Open the LUSC breakdown →

Exploration