RNU6-1234P

Across TCGA pan-cancer cohorts, RNU6-1234P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated RNU6-1234P data layer.

The strongest signal is observed in mesothelioma (MESO), where higher RNU6-1234P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-1234P expression acts as an unfavorable survival marker, although some lineages such as SKCM and HNSC show a favorable association.

MESO, SKCM, and THYM are the cancer types where RNU6-1234P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	II,III,IV	0.160	0.577	.001	99	view →
SKCM	DFS	Tertile	All	0.800	0.604	.003	66	view →
THYM	DFS	Tertile	All	0.123	0.871	<.001	36	view →
THCA	DFS	Tertile	III,IV	0.530	0.904	.004	24	view →
KIRC	DFS	Tertile	IV	0.292	0.647	.002	18	view →
PRAD	OS	Tertile	All	0.956	0.993	.010	12	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →
HNSC	OS	Tertile	II,III,IV	1.000	0.341	.016	9	view →
LIHC	DFS	Tertile	All	0.144	0.555	.030	9	view →
LGG	DFS	Tertile	All	0.651	0.850	.048	3	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

RNU6-1234P–MESO (OS)

Open the MESO breakdown →