RNU6-1234P

Across TCGA pan-cancer cohorts, RNU6-1234P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RNU6-1234P’s most consistent transcriptional readouts.

The strongest signal is observed in esophageal carcinoma (ESCA), where RNU6-1234P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-1234P is over-expressed in tumor, although a few such as ESCA and LUSC show the opposite, repressed pattern.

ESCA and LUSC are the cancer types where RNU6-1234P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-1234P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
ESCA	Female	All	−0.636	.006	1	view →
LUSC	All	All	−0.099	.026	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

RNU6-1234P–ESCA

Open the ESCA breakdown →