RNU6-1231P

Across TCGA pan-cancer cohorts, RNU6-1231P RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated RNU6-1231P data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher RNU6-1231P RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RNU6-1231P expression acts as an unfavorable survival marker, although some lineages such as SKCM and BRCA show a favorable association.

SKCM, ACC, and UVM are the cancer types where RNU6-1231P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Tertile	II,III,IV	0.403	0.200	.001	96	view →
ACC	DFS	Median	All	0.416	0.742	<.001	80	view →
UVM	DFS	Tertile	All	0.287	0.782	.001	54	view →
DLBC	DFS	Tertile	II,III,IV	0.065	0.829	<.001	36	view →
OV	DFS	Quartile	IV	0.308	0.515	.007	20	view →
BRCA	DFS	Tertile	III,IV	0.869	0.755	.019	18	view →
STAD	DFS	Median	III,IV	0.183	0.453	.014	17	view →
THYM	OS	Quartile	All	0.823	1.000	.001	13	view →
READ	DFS	Tertile	All	0.223	0.598	.023	12	view →
PAAD	OS	Tertile	All	0.204	0.404	.026	9	view →
MESO	OS	Tertile	III,IV	0.300	0.459	.028	9	view →
PCPG	DFS	Tertile	All	0.577	0.868	.044	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

RNU6-1231P–SKCM (DFS)

Open the SKCM breakdown →