RNU6-1231P

Across TCGA pan-cancer cohorts, RNU6-1231P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNU6-1231P’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where RNU6-1231P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-1231P is over-expressed in tumor, although a few such as THCA and KIRP show the opposite, repressed pattern.

THCA, KIRP, and PAAD are the cancer types where RNU6-1231P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-1231P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	III,IV	−0.715	<.001	9	view →
KIRP	Male	All	−0.197	.011	5	view →
PAAD	Female	All	−0.750	.037	2	view →
PRAD	All	All	+0.248	.035	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RNU6-1231P–THCA

Open the THCA breakdown →