RNU6-1223P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1223P RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated RNU6-1223P data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher RNU6-1223P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-1223P expression acts as an unfavorable survival marker, although some lineages such as HNSC and BLCA show a favorable association.

ACC, MESO, and LIHC are the cancer types where RNU6-1223P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ACCDFSMedianII,III,IV0.3650.708<.00193view →
MESOOSMedianIV0.3080.847<.00165view →
LIHCDFSTertileAll0.3330.487<.00145view →
HNSCOSMedianIII,IV0.4390.210<.00143view →
THCAOSTertileIII,IV0.5951.000<.00132view →
BLCADFSQuartileIII,IV0.5530.414.01830view →
UCECDFSMedianII,III,IV0.6220.799.00130view →
READOSMedianII,III,IV0.7980.399.00130view →
KICHDFSTertileAll0.5551.000.00425view →
UCSDFSTertileIV0.9380.361.02418view →
KIRCDFSTertileAll0.4580.657.01318view →
ESCAOSMedianAll0.7760.566<.00116view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

RNU6-1223P–ACC (DFS)

Kaplan–Meier survival curve for RNU6-1223P RNA-high vs -low samples in ACC.

Open the ACC breakdown →

Exploration