RNU6-1214P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1214P RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated RNU6-1214P data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher RNU6-1214P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-1214P expression acts as an unfavorable survival marker, although some lineages such as LUAD and LAML show a favorable association.

UVM, READ, and TGCT are the cancer types where RNU6-1214P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UVMOSTertileAll0.1360.919<.00190view →
READDFSTertileAll0.0820.845<.00181view →
TGCTOSTertileII,III,IV0.5051.000<.00160view →
LUADDFSTertileII,III,IV0.9320.657.00745view →
PAADDFSTertileAll0.2240.491.01845view →
UCECDFSTertileIV0.2440.722.00236view →
LAMLDFSMedianAll0.5330.234.00226view →
KIRPDFSTertileIV0.0880.511.00218view →
GBMOSTertileAll0.1950.424.00218view →
LGGOSTertileAll0.1630.453.00218view →
KICHOSTertileIII,IV0.1780.847<.00112view →
STADDFSTertileIV0.0830.379.00112view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

Exploration