RNU6-1206P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1206P RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RNU6-1206P data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher RNU6-1206P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-1206P expression acts as an unfavorable survival marker, although some lineages such as LUSC and MESO show a favorable association.

UVM, LIHC, and PCPG are the cancer types where RNU6-1206P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UVMOSTertileIII,IV0.2110.724<.00169view →
LIHCOSTertileAll0.5660.725.00633view →
PCPGOSTertileAll0.8900.992.00121view →
LUSCDFSTertileIII,IV0.6850.407.01316view →
SKCMDFSTertileIII,IV0.4790.675.02515view →
MESOOSMedianII,III,IV0.7170.485.02910view →
THCADFSMedianIV0.5780.931.0338view →
BLCAOSTertileIV0.4350.214.0475view →
CHOLDFSMedianII,III,IV0.1070.580.0193view →
THYMDFSMedianAll0.8340.984.0293view →
ESCAOSMedianII,III,IV0.6171.000.0493view →
DLBCDFSTertileII,III,IV0.5480.881.0492view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

RNU6-1206P–UVM (OS)

Kaplan–Meier survival curve for RNU6-1206P RNA-high vs -low samples in UVM.

Open the UVM breakdown →

Exploration