RNU6-1206P

Across TCGA pan-cancer cohorts, RNU6-1206P RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of RNU6-1206P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where RNU6-1206P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-1206P is over-expressed in tumor, although a few such as KICH and LUAD show the opposite, repressed pattern.

KICH, HNSC, and LIHC are the cancer types where RNU6-1206P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-1206P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	−0.268	.033	3	view →
HNSC	Female	II,III,IV	+0.180	.034	3	view →
LIHC	All	All	+0.097	.003	3	view →
ESCA	All	II,III,IV	+1.565	.035	2	view →
LUAD	All	IV	−1.265	.047	2	view →
CHOL	Male	All	+0.786	.003	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

RNU6-1206P–KICH

Open the KICH breakdown →