RNU6-1191P

Across TCGA patient cohorts, RNU6-1191P mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. COAD shows the largest number of these associations.

The most reproducible RNU6-1191P-associated genes across cancer lineages are RPS29P26, KYNUP2, and SNORA36C. Each is linked with RNU6-1191P in more than 1 cancer types. Because this analysis shows association rather than direction, both RNU6-1191P-to-partner and partner-to-RNU6-1191P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS29P26 grouped by RNU6-1191P-low versus RNU6-1191P-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-1191P→partner) and Y-score (partner→RNU6-1191P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RPS29P26 →	+0.718	+7.816	<.001	.008	3	1
SKCM	KYNUP2 →	+0.059	+7.816	<.001	.008	3	1
UCEC	SNORA36C →	+0.427	+4.551	<.001	.009	3	1
UCEC	TRAJ20 →	+1.499	+4.499	<.001	.005	3	1
UCEC	RNU6-1077P →	+0.681	+4.188	.003	.009	3	1
UCEC	RN7SKP167 →	+0.332	+5.453	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

RPS29P26 by RNU6-1191P expression — SKCM

Explore this box plot interactively →