RNU6-1170P

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1170P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNU6-1170P’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where RNU6-1170P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU6-1170P is over-expressed in tumor, although a few such as THCA and LUSC show the opposite, repressed pattern.

STAD, THCA, and LUSC are the cancer types where RNU6-1170P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-1170P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
STADMaleAll+0.593.0065view →
THCAAllII,III,IV−0.402<.0015view →
LUSCAllII,III,IV−0.167.0203view →
LUADMaleAll+0.637.0262view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RNU6-1170P–STAD

Tumor-vs-normal expression box plot for RNU6-1170P RNA in STAD.

Open the STAD breakdown →

Exploration