RNU6-1152P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1152P RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RNU6-1152P data layer.

The strongest signal is observed in testicular germ cell tumors (TGCT), where higher RNU6-1152P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-1152P expression acts as an unfavorable survival marker, although some lineages such as HNSC and ESCA show a favorable association.

TGCT, KICH, and UVM are the cancer types where RNU6-1152P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
TGCTOSTertileII,III,IV0.5010.996<.00172view →
KICHOSTertileAll0.1550.926<.00163view →
UVMOSTertileAll0.2200.917<.00154view →
UCSDFSTertileAll0.1640.544.00154view →
PAADOSTertileII,III,IV0.3990.653.00327view →
OVDFSTertileIV0.2870.499.01824view →
HNSCOSTertileAll0.6080.331.01121view →
LIHCOSTertileIII,IV0.1180.615.00318view →
GBMOSTertileAll0.0870.419.00218view →
ACCOSTertileIII,IV0.2080.650.0329view →
COADOSTertileIV0.1400.657.0359view →
THCADFSTertileAll0.8510.950.0139view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

Exploration