RNU6-1152P

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1152P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNU6-1152P’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where RNU6-1152P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU6-1152P is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

BRCA, ESCA, and COAD are the cancer types where RNU6-1152P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-1152P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
BRCAFemaleII,III,IV+0.206.0116view →
ESCAAllII,III,IV+1.055.0152view →
COADAllII,III,IV+0.118.0252view →
KICHAllAll−0.101.0361view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration