Across TCGA pan-cancer cohorts, RNU6-110P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNU6-110P’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where RNU6-110P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU6-110P is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

STAD, LUAD, and THCA are the cancer types where RNU6-110P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-110P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	All	All	+0.238	.001	5	view →
LUAD	Female	All	+0.188	.015	2	view →
THCA	All	All	−0.100	.009	2	view →
KIRC	Male	All	+0.090	.033	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RNU6-110P RNA expression & survival · all RNU6-110P data types