RNU6-1099P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1099P RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated RNU6-1099P data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RNU6-1099P RNA is associated with better overall survival. In most high-consensus cancer types, elevated RNU6-1099P expression acts as an unfavorable survival marker, although some lineages such as HNSC and READ show a favorable association.

HNSC, UVM, and UCEC are the cancer types where RNU6-1099P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCOSMedianIV0.8190.647.00239view →
UVMDFSQuartileIII,IV0.1110.808<.00130view →
UCECDFSTertileAll0.7900.887.00328view →
MESODFSTertileAll0.3880.769.00624view →
ACCDFSMedianAll0.4530.753.00622view →
LGGOSTertileAll0.7410.900.00418view →
READDFSMedianIII,IV0.6520.363.01013view →
LIHCDFSQuartileAll0.4590.619.01112view →
PRADDFSTertileAll0.7410.817.02412view →
SKCMOSQuartileIII,IV0.7900.554.00711view →
KICHDFSMedianIII,IV0.2700.803.0046view →
STADDFSQuartileIII,IV0.4240.682.0156view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

Exploration