RNU6-1086P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1086P RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated RNU6-1086P data layer.

The strongest signal is observed in mesothelioma (MESO), where higher RNU6-1086P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-1086P expression acts as an unfavorable survival marker, although some lineages such as UCS and BRCA show a favorable association.

MESO, UCEC, and COAD are the cancer types where RNU6-1086P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
MESODFSTertileII,III,IV0.2010.442.00290view →
UCECDFSTertileAll0.7320.902.00542view →
COADOSTertileIII,IV0.0560.781<.00127view →
OVOSTertileIV0.5900.862.00122view →
LUSCOSTertileII,III,IV0.2570.741<.00118view →
UCSDFSTertileII,III,IV1.0000.244.03312view →
STADDFSTertileIV0.0830.379.0019view →
LUADOSTertileII,III,IV0.2530.590.0339view →
LGGDFSQuartileAll0.2670.444.0136view →
BRCADFSTertileIII,IV0.9470.467.0406view →
THCAOSTertileIV0.8380.977.0223view →
Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

Exploration