RNU6-1061P

Across TCGA pan-cancer cohorts, RNU6-1061P RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of RNU6-1061P’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where RNU6-1061P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-1061P is over-expressed in tumor, although a few such as LUSC and KIRC show the opposite, repressed pattern.

LUSC, KIRC, and BRCA are the cancer types where RNU6-1061P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-1061P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	−0.438	<.001	7	view →
KIRC	All	All	−0.236	<.001	7	view →
BRCA	All	III,IV	−0.702	<.001	6	view →
THCA	All	All	−0.431	<.001	3	view →
KICH	All	All	−0.355	.006	3	view →
CHOL	Female	All	+2.420	.028	2	view →
STAD	Male	All	+0.240	.016	2	view →
LUAD	All	III,IV	−0.444	.048	1	view →
COAD	All	III,IV	+0.267	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

RNU6-1061P–LUSC

Open the LUSC breakdown →