RNU6-1061P

associated omics data
RNA, U6 small nuclear 1061, pseudogeneGenealiases: []

Q-omics provides the consensus-scored RNU6-1061P profile across patient tissues and cancer cell-line models. RNU6-1061P expression is associated with patient survival in 16 of 34 cancer types, with the highest sampling consensus in MESO. Among the 18 cancer types available for tumor–normal comparison, RNU6-1061P is differentially expressed in 9, with the highest sampling consensus in LUSC. Additionally, RNU6-1061P RNA expression shows 10,020 significant gene co-expression associations, with the highest sampling consensus in CESC. Together, these results highlight MESO, LUSC, and CESC as cancer lineages where RNU6-1061P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes RNU6-1061P survival associations across molecular data types. RNU6-1061P RNA expression shows survival associations in the most cancer types (16). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
RNU6-1061P data typeSurvival analysisLineage consensusLineage of highest sampling consensus
RNAKaplan–Meier16MESO (83)view →
This table ranks reproducible RNU6-1061P RNA expression–survival associations across cancer types. High RNU6-1061P expression shows unfavorable associations in HNSC and DLBC, but favorable associations in MESO, ACC, BRCA and STAD. The MESO Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify MESO as the clearest survival context for RNU6-1061P RNA expression.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
MESOOSMedianAll0.6840.438<.00183view →
ACCOSTertileIII,IV0.8560.470.00954view →
BRCADFSMedianIII,IV0.5140.463.01226view →
HNSCDFSTertileAll0.3940.608.02718view →
DLBCOSTertileAll0.4730.945.00618view →
STADOSTertileIII,IV0.7020.371.02112view →
Pink = unfavorable, green = favorable. all 16 lineages →

RNU6-1061P-MESO (OS)

Kaplan–Meier survival curve for RNU6-1061P RNA expression in MESO: high vs low expression groups.

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Tumor vs Normal expression

This table summarizes RNU6-1061P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 9. The strongest signals are observed in LUSC for RNA.
RNU6-1061P data typeExpression analysisLineage consensusLineage of highest sampling consensus
RNABox plot9LUSC (7)view →
This table ranks reproducible tumor–normal expression differences for RNU6-1061P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU6-1061P shows lower tumor expression in LUSC, KIRC, BRCA, THCA and KICH and higher tumor expression in CHOL. The LUSC box plot shows higher RNU6-1061P RNA expression in normal versus tumor tissue (log2 FC = −0.438, t-test p < 0.001).
LineageGenderStageFold-changepSampling consensus
LUSCAllAll−0.438<.0017view →
KIRCAllAll−0.236<.0017view →
BRCAAllIII,IV−0.702<.0016view →
THCAAllAll−0.431<.0013view →
KICHAllAll−0.355.0063view →
CHOLFemaleAll+2.420.0282view →
Green = repressed in tumor. all 9 lineages →

RNU6-1061P-LUSC

Tumor-vs-normal expression box plot for RNU6-1061P in LUSC.

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Cross-omics associations

This table shows molecular features associated with RNU6-1061P in patient tissues and cancer cell lines. In patient samples, RNU6-1061P shows the broadest associations at the RNA and protein expression levels, with CESC recurring as the lineage with the largest associated feature set.
Associated data typeStrength (# associated data)Lineage of highest associated data
RNA
RNA10,020CESC (3545)view →
Protein (mass-spec)7,270UCEC (1216)view →