RNU6-1057P

Across TCGA pan-cancer cohorts, RNU6-1057P RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated RNU6-1057P data layer.

The strongest signal is observed in testicular germ cell tumors (TGCT), where higher RNU6-1057P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-1057P expression acts as an unfavorable survival marker, although some lineages such as GBM and BLCA show a favorable association.

TGCT, DLBC, and UCS are the cancer types where RNU6-1057P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
TGCT	OS	Tertile	All	0.770	0.976	<.001	72	view →
DLBC	OS	Tertile	II,III,IV	0.172	0.949	<.001	54	view →
UCS	OS	Tertile	III,IV	0.001	0.594	<.001	36	view →
THCA	DFS	Tertile	All	0.837	0.943	<.001	36	view →
CESC	DFS	Tertile	II,III,IV	0.582	0.803	.024	36	view →
ACC	OS	Tertile	All	0.180	0.709	.012	36	view →
LIHC	OS	Tertile	All	0.368	0.709	.002	27	view →
GBM	DFS	Tertile	All	0.429	0.175	.004	18	view →
SKCM	OS	Tertile	IV	0.179	0.727	<.001	18	view →
ESCA	DFS	Median	IV	0.213	0.626	.026	15	view →
LGG	OS	Tertile	All	0.838	0.924	.012	12	view →
OV	OS	Quartile	All	0.803	0.862	.027	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

RNU6-1057P–TGCT (OS)

Open the TGCT breakdown →