RNU6-1057P

Across TCGA pan-cancer cohorts, RNU6-1057P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RNU6-1057P’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where RNU6-1057P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU6-1057P is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.

BLCA, COAD, and ESCA are the cancer types where RNU6-1057P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-1057P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	All	+0.222	.017	2	view →
COAD	Male	All	−0.157	.038	2	view →
ESCA	All	All	+0.613	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

RNU6-1057P–BLCA

Open the BLCA breakdown →