RNU6-104P

Across TCGA patient cohorts, RNU6-104P mutation is significantly associated with the RNA expression of many other genes, with 82 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible RNU6-104P-associated genes across cancer lineages are LINC02420, NEK4P2, and RNU6-642P. Each is linked with RNU6-104P in more than 1 cancer types. Because this analysis shows association rather than direction, both RNU6-104P-to-partner and partner-to-RNU6-104P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02420 grouped by RNU6-104P-low versus RNU6-104P-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-104P→partner) and Y-score (partner→RNU6-104P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LINC02420 →	+0.077	+4.402	<.001	.002	3	2
SKCM	NEK4P2 →	+0.027	+4.614	<.001	.006	3	2
HNSC	RNU6-642P →	+0.502	+4.565	<.001	.004	3	2
HNSC	GAGE2E →	+0.251	+5.608	<.001	.002	3	2
SKCM	MIR505 →	+0.226	+6.643	<.001	<.001	3	2
SKCM	RNU6-488P →	+0.290	+6.225	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 82 associations by consensus.

LINC02420 by RNU6-104P expression — SKCM

Explore this box plot interactively →