RNU6-1048P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1048P RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated RNU6-1048P data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RNU6-1048P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-1048P expression acts as an unfavorable survival marker, although some lineages such as UCS and BRCA show a favorable association.

UCEC, UCS, and COAD are the cancer types where RNU6-1048P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECDFSMedianAll0.5410.719<.00190view →
UCSDFSMedianIV0.9520.367.00146view →
COADDFSTertileAll0.4290.770<.00131view →
UVMDFSQuartileIII,IV0.3020.715.00430view →
ACCDFSQuartileII,III,IV0.3320.741.00724view →
BRCADFSMedianIII,IV0.9280.823.00923view →
KIRPDFSMedianAll0.8040.905.00622view →
CESCDFSMedianAll0.7690.874.00320view →
READOSMedianAll0.7830.317.00418view →
LUSCOSMedianAll0.8130.739.01912view →
CHOLOSQuartileII,III,IV0.2021.000.02412view →
SARCOSMedianAll0.4530.708.00611view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

Exploration