RNU5B-3P

Across TCGA pan-cancer cohorts, RNU5B-3P RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated RNU5B-3P data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher RNU5B-3P RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RNU5B-3P expression acts as an unfavorable survival marker, although some lineages such as ACC and THCA show a favorable association.

ACC, MESO, and DLBC are the cancer types where RNU5B-3P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.820	0.587	.010	31	view →
MESO	OS	Tertile	All	0.174	0.577	.006	27	view →
DLBC	DFS	Tertile	III,IV	0.070	0.855	.008	18	view →
TGCT	OS	Tertile	II,III,IV	0.795	1.000	.039	18	view →
BRCA	DFS	Quartile	All	0.570	1.000	.045	12	view →
THCA	DFS	Tertile	IV	1.000	0.563	.016	12	view →
KICH	DFS	Tertile	IV	0.317	0.923	.038	10	view →
SKCM	DFS	Tertile	IV	0.943	0.159	.031	9	view →
ESCA	OS	Tertile	III,IV	0.777	0.499	.030	8	view →
LUAD	OS	Tertile	III,IV	0.687	0.423	.044	8	view →
BLCA	OS	Tertile	All	0.802	0.691	.033	6	view →
KIRC	DFS	Median	IV	0.708	0.560	.039	2	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

RNU5B-3P–ACC (DFS)

Open the ACC breakdown →