RNU5A-3P

Across TCGA pan-cancer cohorts, RNU5A-3P RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated RNU5A-3P data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher RNU5A-3P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU5A-3P expression acts as an unfavorable survival marker, although some lineages such as PRAD and LAML show a favorable association.

LIHC, CHOL, and KICH are the cancer types where RNU5A-3P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Tertile	III,IV	0.243	0.670	<.001	72	view →
CHOL	OS	Tertile	All	0.142	0.761	<.001	66	view →
KICH	OS	Tertile	II,III,IV	0.070	0.828	<.001	54	view →
KIRC	OS	Tertile	II,III,IV	0.386	0.563	.006	39	view →
LUSC	DFS	Tertile	II,III,IV	0.558	0.737	.002	36	view →
ACC	OS	Tertile	III,IV	0.189	0.764	.004	30	view →
READ	DFS	Tertile	IV	0.082	0.619	.001	24	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
MESO	OS	Tertile	IV	0.077	0.592	.019	18	view →
KIRP	DFS	Tertile	II,III,IV	0.125	0.655	.028	18	view →
LUAD	DFS	Tertile	IV	0.047	0.565	<.001	18	view →
SKCM	OS	Tertile	IV	0.179	0.727	<.001	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

RNU5A-3P–LIHC (OS)

Open the LIHC breakdown →