RNU4-49P

Across TCGA pan-cancer cohorts, RNU4-49P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RNU4-49P data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher RNU4-49P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU4-49P expression acts as an unfavorable survival marker, although some lineages such as LUAD and SKCM show a favorable association.

BLCA, OV, and UCEC are the cancer types where RNU4-49P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	All	0.406	0.619	.004	147	view →
OV	OS	Tertile	II,III,IV	0.608	0.859	<.001	108	view →
UCEC	OS	Tertile	IV	0.066	0.755	<.001	66	view →
UVM	DFS	Tertile	All	0.079	0.746	<.001	54	view →
UCS	OS	Tertile	II,III,IV	0.096	0.629	.002	54	view →
LUAD	DFS	Tertile	All	0.662	0.330	.023	42	view →
CHOL	OS	Tertile	All	0.218	0.676	.020	18	view →
DLBC	DFS	Tertile	All	0.399	0.796	.032	18	view →
ACC	DFS	Tertile	II,III,IV	0.226	0.725	.009	18	view →
LIHC	DFS	Tertile	III,IV	0.081	0.413	.048	9	view →
SARC	OS	Tertile	All	0.206	0.531	.012	6	view →
SKCM	OS	Tertile	All	0.427	0.303	.044	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

RNU4-49P–BLCA (OS)

Open the BLCA breakdown →