Q-omics provides the consensus-scored RNU4-20P profile across patient tissues and cancer cell-line models. RNU4-20P expression is associated with patient survival in 4 of 34 cancer types, with the highest sampling consensus in HNSC. Additionally, RNU4-20P RNA expression shows 6,585 significant gene co-expression associations, with the highest sampling consensus in ESCA. Together, these results highlight HNSC, and ESCA as cancer lineages where RNU4-20P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes RNU4-20P survival associations across molecular data types. RNU4-20P RNA expression shows survival associations in the most cancer types (4). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

RNU4-20P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	4	HNSC (81)	view →

This table ranks reproducible RNU4-20P RNA expression–survival associations across cancer types. High RNU4-20P expression shows unfavorable associations in HNSC, UCEC and STAD, but favorable associations in ESCA. The HNSC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify HNSC as the clearest survival context for RNU4-20P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	II,III,IV	0.082	0.711	<.001	81	view →
UCEC	OS	Tertile	II,III,IV	0.204	0.768	.003	72	view →
STAD	OS	Tertile	All	0.142	0.735	<.001	63	view →
ESCA	OS	Tertile	III,IV	1.000	0.372	.033	12	view →

Pink = unfavorable, green = favorable. all 4 lineages →

RNU4-20P-HNSC (OS)

Kaplan–Meier survival curve for RNU4-20P RNA expression in HNSC: high vs low expression groups.

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Cross-omics associations

This table shows molecular features associated with RNU4-20P in patient tissues and cancer cell lines. In patient samples, RNU4-20P shows the broadest associations at the RNA and protein expression levels, with ESCA recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	6,585	ESCA (3687)	view →
Function (RNA)	4,953	STAD (4936)	view →