RNU2-58P

Across TCGA patient cohorts, RNU2-58P RNA expression is significantly associated with the go_rna of many other GO terms, with 6,699 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU2-58P-associated GO terms across cancer lineages are Positive regulation of DNA metabolic process, Epigenetic regulation of gene expression, and Centrosome duplication. Each is linked with RNU2-58P in more than 21 cancer types. Because this analysis shows association rather than direction, both RNU2-58P-to-partner and partner-to-RNU2-58P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA metabolic process grouped by RNU2-58P-low versus RNU2-58P-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU2-58P→partner) and Y-score (partner→RNU2-58P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of DNA metabolic process →	+0.052	+0.452	<.001	<.001	3	22
STAD	Epigenetic regulation of gene expression →	+0.055	+0.500	<.001	<.001	3	21
ESCA	Centrosome duplication →	+0.052	+0.442	<.001	<.001	3	21
ESCA	DNA replication →	+0.056	+0.556	<.001	<.001	3	21
STAD	Regulation of DNA repair →	+0.049	+0.446	<.001	<.001	3	21
STAD	Double-strand break repair via nonhomologous end joining →	+0.050	+0.492	<.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,699 associations by consensus.

Positive regulation of DNA metabolic process by RNU2-58P expression — STAD

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